Settling in
You may notice mild digestive changes as the strains settle in. This is usually temporary, a sign things are getting started.*

Advanced TriSynbiotic™

Reset your gut
A million microbiomes taught us one thing:
Almost every gut needs the same few fundamentals working together. So we built all five into one daily capsule — a postbiotic, three probiotics, and butyrate delivered direct, each one engineered to reach where it works.

Advanced TriSynbiotic™ is the foundation we'd put under any gut — one capsule a day, built from what the data showed.

Most gut supplements start with general assumptions about what tends to work. We started with what sequencing over a million microbiomes actually revealed, then let that decide what goes in the formula, and what doesn't.
Every ingredient is clinically studied and earned its place. Nothing is here by default.
Others bet on a single hero strain to shift your whole system. The data points elsewhere. Almost every gut benefits from the same few fundamentals working together, and when they're in place, everything else has somewhere solid to build from. Advanced TriSynbiotic™ supports all three, every day.





30 CAPSULES | 1-MONTH SUPPLY
A Daily Foundation for a Stronger Gut Lining
A once-daily 5-in-1 capsule that supports the gut foundation everything else runs on. Built from over a million sequenced microbiomes, Advanced TriSynbiotic™ combines a postbiotic, three targeted probiotics, and direct butyrate delivery to support digestion, metabolism, and appetite. Engineered to reach where they actually work.*
A stronger gut foundation*
Supports your gut lining and a balanced, resilient mix of good bacteria, so digestion stays comfortable and your gut bounces back from everyday ups and downs.*
Metabolic and blood sugar balance support*
Supports healthy glucose metabolism and blood sugar already within the normal range, the everyday balance your energy depends on.*
Appetite support*
Supports a healthy appetite and complements a GLP-1 diet and lifestyle.*

The gut doesn't work alone. It talks to your immune system and your brain every day, and Advanced TriSynbiotic™ was built to support that whole conversation.*
Immune support*
Supports a healthy immune response and helps reinforce the tight junctions in your gut lining that support a healthy immune system.*
Mood, stress, and sleep*
Lp815 produces GABA over time to support a calm mood, a healthy stress response, and better sleep quality.*
Focus and mental clarity*
Through the gut-brain axis, the same ingredients that fuel your gut also support focus and everyday mental clarity.*

Akkermansia
Akkermansia is everywhere right now, and almost always used live. That means it has to survive your stomach and settle in before it can do anything. A lot of it never makes the trip.*
We took the more reliable route. Advanced TriSynbiotic™ uses a postbiotic form of Akkermansia, ready to work the moment it arrives, no survival required. You get the benefit Akkermansia is known for, a stronger gut lining, without leaving it to chance.*
Live strains have to survive. A postbiotic doesn't. A more dependable way to support your gut lining.*

Butyrate is the fuel your gut lining runs on. When it runs low, your gut has less to work with. Most products hope your body makes enough on its own. We don't leave it to hope. We do both:*
Butyrate-producing bacteria are sometimes called the "sentinels of the gut." They help keep unwanted microbes from taking hold and help keep your gut environment calm and balanced.*

Make more
A targeted butyrate-producing strain, Anaerobutyricum soehngenii, turns fiber into butyrate, building a steady supply over time.*
Deliver it direct
CoreBiome® Tributyrin sends butyrate straight where it's needed, so your gut is supported right away.*
Strengthen the lining
That butyrate fuels and strengthens your gut lining, the barrier that keeps digestion comfortable.*
Build a foundation that holds
The result: a stronger gut foundation that also supports steady energy, blood sugar already within the normal range, and a healthy appetite, day to day.*
What That Means For You
More butyrate, a better-protected gut lining. The kind of difference you may feel as steadier digestion and everyday comfort. Butyrate now, and butyrate later.*
You may notice mild digestive changes as the strains settle in. This is usually temporary, a sign things are getting started.*
Your gut is being supported and reinforced. Some people feel early benefits in this window. Results vary from person to person.*
With daily use, your gut runs steadier. A foundation for comfortable digestion and everyday wellness. Keep going to keep it strong.*
Nothing here by default. Each ingredient is clinically studied and was chosen because a million microbiomes pointed to it, then protected by patented DuoCap® delivery so it reaches the part of your gut where it works.*

OUTER CAPSULE
Sends butyrate straight to the colon to fuel and strengthen your gut lining, and help support a healthy inflammatory response in the gut.*
INNER CAPSULE
Supports a stronger gut lining, and works in the small intestine too. Because it's a postbiotic, it's ready to work without surviving the trip.*
One of the most abundant butyrate producers in the small intestine. Turns fiber and sugars into beneficial butyrate, part of how a healthy gut supports a healthy appetite and blood sugar already within the normal range.*
Supports a balanced mix of good bacteria and a healthy immune system.*
Releases GABA over time for added calm, better sleep, and stress support.*
Simple to take
Just one capsule daily. An easy habit that supports your gut from the inside out.*
Built to last
Daily use keeps your gut steady and well-supported over time.*
Protected delivery
DuoCap® protects the ingredients and gets them to the right place at the right time.*

A strong gut foundation, one capsule a day.*
Questions, answered.



Support the gut foundation everything else depends on,* with Advanced TriSynbiotic™. One capsule a day. And when you're ready to go deeper into your own biology, we'll be right here.
Advanced TriSynbiotic™
[1] Marzorati M, Calatayud M, Rotsaert C, et al. Comparison of protection and release behavior of different capsule polymer combinations based on L. acidophilus survivability and function and caffeine release. Int J Pharm. 2021;607:120977. doi:10.1016/j.ijpharm.2021.120977
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. The information Viome provides is for educational and informational use only and is not a substitute for professional medical advice. Available to US customers only, ages 14+.
UP TO 46X MORE EFFECTIVE
It's just one capsule a day, engineered as a capsule-in-capsule. Patented DuoCap® technology delivers the ingredients up to 46X more effectively than conventional probiotic capsules [1], protecting them from stomach acid and releasing them in both the small and large intestine, where they actually work.
Microbiomes sequenced. The knowledge base behind the formula.
Three probiotics, a postbiotic, and butyrate delivered direct, in one capsule.
More effective delivery than conventional probiotic capsules, to both the small and large intestine. [1]
Made to support a GLP-1 diet and lifestyle.*
Akkermansia that's ready to work, no survival required.
Made by a butyrate-producing strain and delivered direct by CoreBiome®.*
One simple capsule, diet-compatible.*